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Dermalogica Phyto Nature E² Regenerating Daily Exosome Leave-on Treatment

Dermalogica Phyto Nature E² Regenerating Daily Exosome Leave-on Treatment

Name: Dermalogica Phyto Nature E² Regenerating Daily Exosome Leave-on Treatment
Brand: Dermalogica
SKU: 111518
Price: 212.8 AUD
Availability: InStock
Rating: 1.5 (2 reviews)

Best for: menopause, ageing, all skin types

Rated 1.5 out of 5

Based on 2 reviews

Earn up to points with this purchase!

A next-gen bioactive serum that resurfaces and regenerates in one step. Dermalogica Phyto Nature E² Regenerating Daily Exosome Leave-on...Read more

$212.80$266

Pay in 4 instalments of $53.20

Or 4 interest-free payments of $53.20

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Anti-Ageing

Exfoliating

Firming

Rejuvenating

Skin Brightening

Use in: AM & PM

How to use

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Full Description

A next-gen bioactive serum that resurfaces and regenerates in one step.

Dermalogica Phyto Nature E² Regenerating Daily Exosome Leave-on Treatment is a daily leave-on liquid treatment powered by plant-derived exosomes, pumpkin enzymes, and firming botanicals.

It smooths, brightens and revitalises while respecting sensitive, ageing or menopausal skin. Ideal for dry, dull, sensitised or post-retinol skin.

How It Works

This isn’t just skincare – it’s cellular coaching. Phyto Nature E² Regenerating Daily Exosome Leave-on Treatment uses botanical exosomes from turmeric and acacia to help your skin behave younger, visibly reversing signs of biological ageing. These plant-derived messengers enter skin cells, easing inflammation, increasing resilience, and boosting radiance over time.

Pumpkin ferment delivers instant glow by gently digesting dead skin without the harshness of acids, making it perfect for those who are fatigued by retinol or struggle with dryness and flaking. Acacia gum tightens instantly for a subtle lift, while acetyl glucosamine supports hydration from within.

Whether you’re navigating hormonal skin shifts, calming inflammation, or simply want better performance from your routine, Phyto Nature E² Regenerating Daily Exosome Leave-on Treatment fits in seamlessly as a ‘prep and treat’ booster step. Think of it as a reset for stressed, tired skin – the new must-have for menopausal skin, barrier-compromised users or the “skintellectual” minimalist.

- Supports the skin’s natural renewal and resilience with exosomes

- Instantly smooths and softens with enzymatic exfoliation

- Reduces signs of stress and fatigue for a more radiant glow

- Firms and hydrates with bio-lifting botanical actives

- Strengthens skin barrier without irritation – perfect post-retinol or post-treatment

Ingredients

Turmeric Stem Cell Exosomes: Deliver potent antioxidant and anti-inflammatory actives to help restore resilience, reduce redness, and modulate ageing pathways linked to stress and hormonal shifts.

Pumpkin Ferment Enzymes: A gentle, self-limiting exfoliant that digests only dead skin cells—no irritation, no over-stripping—leaving skin instantly smoother and more radiant.

Acacia Senegal Gum: Forms an invisible mesh on the skin’s surface, providing a subtle lifting and tightening effect while also soothing sensitivity.

Acetyl Glucosamine: Supports hyaluronic acid production within the skin and inhibits pigmentation pathways—hydrating from within and evening out tone over time.

Prickly Pear Extract: Rich in vitamins, polyphenols and essential fatty acids, this hydrating extract improves skin elasticity, reduces transepidermal water loss, and enhances glow.

FULL INGREDIENTS: Water/Aqua/Eau, Glycerin, Butylene Glycol, Lactobacillus/Pumpkin Fruit Ferment Filtrate, Acetyl Glucosamine, Propanediol, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Prickly Pear Cactus Extract, Curcuma Longa (Turmeric) Callus Conditioned Media, Acacia Senegal Gum, Glycogen, Betaine, Saccharide Isomerate, Caprylyl Glycol, Ethylhexylglycerin, 1,2-Hexanediol, Hydroxyacetophenone, Citric Acid, Xanthan Gum, Sodium Citrate, Biosaccharide Gum-1, Disodium EDTA, Parfum/Fragrance.

Shipping & Returns

FREE for orders $49+ via Australia Post e-Parcel ground.

Express Air add $5.95.

Same Day Dispatch by 4pm M-F (Sydney Business Days)

Returns

If something isn’t quite right, you can lodge a return through our Returns Portal.

Our team will review your request and guide you through the next steps.

Please note: Change of mind returns are only accepted for products that are unopened, unused, and in their original sealed packaging

All returns must be lodged through the portal and approved prior to sending any items back

Tutorial

Step-by-step

1

CleanseUse a mild, non-stripping cleanser to remove impurities and prep the skin. Clean skin allows active ingredients to penetrate more effectively in the steps that follow.

2

Tone & BalanceApply a hydrating toner or essence to restore pH balance and prime the skin for better absorption of treatment serums. Look for formulas with soothing or replenishing botanicals.

3

Apply Phyto Nature E² Regenerating Daily Exosome Leave-on TreatmentApply Phyto Nature E² Regenerating Daily Exosome Leave-on Treatment – 2–3 pumps pressed gently into skin. This lightweight liquid absorbs quickly to infuse exosomes and enzymes, supporting cell renewal and calming irritation.

4

Lock in MoistureFollow with a moisturiser suited to your skin type. This seals in the actives from previous steps and delivers long-lasting hydration and barrier support, especially for ageing skin.

5

Protect with SPFIn the morning, always finish with a broad-spectrum SPF 30 or higher. This protects the skin against photoageing, UV damage and prevents undoing the benefits of your treatment.

Write a Review

average rating 1.5 out of 5

Based on 2 reviews

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2 Reviews

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Reviewed by khatija h.

Verified Buyer

I don't recommend this product

Age Range

35 - 44

Skin Concerns

Ageing

Did you notice a difference in your skin?

No

Rated 1 out of 5

Review posted

Not worth the price

Haven’t noticed any difference to my skin…in fact, I think that the fine lines are more prominent since I started using this product with the oxygen cream and cleanser than with the product I previously used

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Aroma/Scent	Rated 3 out of 5
Texture on Skin	Rated 4 out of 5
Value for Money	Rated 1 out of 5

Was this helpful?

Skinmart

Thank you for taking the time to share your feedback. We understand it can be disappointing not to see the results you were hoping for.

Whilst the Phyto Nature E² can take time to deliver visible improvements, there are also other factors we like to consider. The formula encourages skin renewal, and during the cooler months this can sometimes highlight underlying dehydration, making fine lines appear more noticeable temporarily.
As every skin is different, we'd love the opportunity to review your skincare routine and ensure the product is the right fit for your skin's current needs. Please feel free to contact our team so we can provide personalised advice and help you achieve the best possible results.

Reviewed by KCHERIE

Verified Buyer

I don't recommend this product

Rated 2 out of 5

Review posted

An expensive product to play "will it, wont it" work!

To give this review context I have aging sensitive skin that is dry on the cheekbones, normal/oily in the t-zone and normal for the rest of the face. I have been using Dermalogica products for over twelve years so when I read the description on Dermalogica's new Phyto Nature E² I thought perfect this sounds like it would cover all the concerns my skin has.

After the first week I noticed no difference, it didn't effect my sensitivity as promised, but my face also didn't feel smoother to the touch.

I have now been using the product for almost two months - when I do my skincare I pre-cleanse, cleanse, use toner, the serum then moisturise every morning and night, its my way of winding down at night and feeling clean after the day had past, in addition when I use serum I rub the left over product into my elbows so its not wasted (I do the same for the moisturiser) and at night when I go to bed i also moisturise my elbows with a sensitive body moisturiser (I have been doing this for years) - when I was doing that I started to notice that my elbows have dry skin patches the size of a twenty cent piece on them, I dismissed it thinking I had been in a lot of air conditioned buildings and that doesn't help but as I started to be more conscience of this I realised that my cheekbones that I have had a problem with dryness are feeling dryer and the serum does not appear to be helping them.

I will state the the t-zone has been okay but the rest of my face feels drier to the point…

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Was this helpful?

Skinmart

Hi K,Cherie,

Thank you for taking the time to share such a detailed and thoughtful review.

We’re sorry to hear that the Phyto Nature E² Regenerating Treatment hasn’t been the right fit for your skin, particularly given your long-standing experience with Dermalogica. We truly appreciate the context you’ve provided around your skin type and routine, it’s incredibly helpful.

From what you’ve described, it sounds like your skin may not have responded as expected to this formulation, particularly in terms of hydration and barrier support, which is so important for sensitive and drier areas. While this product is designed to target multiple concerns, some skins, especially those that are more delicate or lipid-dry, may require a more intensive barrier-repair approach rather than a multi-correction treatment.

We also appreciate you noting the changes not only on your face but on areas like your elbows, this kind of awareness is so valuable and clearly shows how in tune you are with your skin.

It’s completely understandable that you’ve returned to your UltraCalming Serum, as this range is specifically designed to support sensitivity and barrier health, which may be more aligned with what your skin is currently needing.

Your feedback is incredibly valuable, particularly for clients with similar skin types considering this product. If you would like to reach out to hello@skinmart.com.au as Dermalogica has a satisfactory guarantee.

Thank you again for your honesty and for sharing your experience so thoroughly.