Peptides 101

If skincare ingredients were characters in a novel, peptides would be the quietly brilliant ones — the dependable supporting cast that makes everything work better. These microscopic messengers don’t shout; they orchestrate. Under the skin’s surface they direct repair, signal for new collagen and elastin, and help your barrier hold steady. The result: skin that looks firmer, smoother and more resilient over time.

Here we break down what peptides are, the key types to know, why formulation matters, and how to get the best results from peptide serums like Medik8 Liquid Peptides Advanced MP.

Think of your skin as a busy city. Collagen is the skyline’s framework; elastin gives the buildings flexibility; hydration is the power grid keeping everything functioning. Peptides are the text messages between the city planners — tiny signals telling skin cells when to build, repair or protect.

As we age (starting in our 20s), those messages slow. Fewer instructions mean slower repair and weaker structure — and over time the city shows it: fine lines, loss of firmness and dullness. Topical peptides step in to restart the conversation, nudging cells back into productive behaviour without the irritation some stronger actives can cause.

Quick takeaway: peptides are gentle, behaviour-changing molecules that support structure and comfort — great for both prevention and repair.

Peptides aren’t dramatic, but they’re effective. When formulated and delivered well, they deliver:

• More collagen & firmer skin — signal peptides encourage fibroblasts (the skin’s builders) to make collagen and elastin.

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• Smoother lines & expression softening — neuro-mimetic peptides relax micro-muscle activity, blurring movement lines.

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• Better barrier & less redness — some peptides and prebiotic blends strengthen lipids, reducing sensitivity and water loss.

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• Faster recovery after procedures — carrier peptides (like copper complexes) support healing and tissue repair.

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• Low irritation — compared with stronger actives, peptides are generally well tolerated.

Not all peptides have the same job. Here are the main families and what they do:

• Signal peptides — the “coaches.” They tell fibroblasts to produce collagen and elastin. Think firmness and improved skin architecture.

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• Carrier peptides — the “delivery drivers.” They transport trace elements (like copper) essential for protein synthesis and healing.

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• Neuro-mimetic peptides — the “relaxers.” They modulate muscle micro-activity to soften expression lines (a topical, non-invasive approach).

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• Enzyme-inhibitor peptides — the “protectors.” They help prevent enzymes from breaking down existing collagen.

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• Barrier-support peptides — the “comfort crew.” They calm inflammation and support lipid repair for better hydration and tolerance.

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Most modern serums combine several classes for broader, multi-pathway benefits.

A great peptide serum is more than a list of names — it’s about concentration, complementary actives, and a delivery system that reaches where it matters. Medik8 Liquid Peptides Advanced MP is engineered around that idea:

• 30% multi-peptide complex — a high-potency blend designed to tackle both quick expression smoothing and longer-term structural remodelling.

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• Dual MiniProtein™ technology — combines expression-line MiniProtein™ for fast softening with Growth Factor MiniProtein™ to stimulate collagen and hyaluronic acid production.

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• Micro-filler hyaluronic acid — multi-weight HA plumps lines and gives immediate sensory smoothing.

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• 1% prebiotic complex — supports the skin barrier and reduces the risk of irritation when layering other actives.

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• Antioxidants — protect against environmental stressors that accelerate ageing.

Peptides are simple to add, but they come alive when used the right way. Follow these rules:

1. 1. Layer on slightly damp skin — apply peptide serums after cleansing while skin is still a little damp. Moist skin helps actives absorb. Then seal with a moisturiser.

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3. 2. Pair thoughtfully — peptides play well with hyaluronic acid, niacinamide and antioxidants. Avoid pairing them immediately with very strong acid exfoliants; either alternate nights or wait 20–60 minutes if you must combine.

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5. 3. Be consistent & protect — peptides build tissue over time. Use daily where tolerated, and always finish your AM routine with SPF — sun protection preserves peptide gains.

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Pro tip: after professional treatments (needling, lasers), use peptide serums and barrier-supporting creams to encourage collagen laydown and speed recovery — but always follow your clinician’s guidance.

Peptides aren’t instant miracle workers, but they do give fast sensory benefits and progressive structural changes:

• First 1–2 weeks: improved hydration and smoother skin feel.

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• 4–8 weeks: visible softening of texture and reduction in fine lines.

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• 12+ weeks: stronger contours and firmer skin with ongoing use.

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Think of peptides like a sustainable fitness program for your skin — early wins appear fast, but the real transformation comes with consistent care.

Peptides are versatile and broadly compatible, but they’re especially valuable for:

• People in their 30s+ looking to slow collagen loss.

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• Post-procedure clients wanting faster, gentler recovery.

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• Anyone with sensitive or reactive skin seeking anti-ageing without irritation.

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• Prevention fans who want to protect and strengthen early.

Peptides are quiet, powerful and dependable — the perfect long-game ingredient for healthy, resilient skin. Start gently, use consistently, and let the small messages bring big results.